Endometriosis: Leuprolide Acetate With Add–Back

Single-Yellow-Girl Leuprolide acetate ( Lupron Depot® ) is a type of gonadotropin–releasing hormone agonist ( GnRH protagonist ) music. GnRH agonist medications help to lower pelvic pain caused by endometriosis. Add–back therapy is the summation of a humble amount of progesterone with or without estrogen. You must take add–back therapy if you are prescribed Leuprolide acetate rayon ) .

How does Leuprolide acetate work?

This medication works by shutting off hormones made by your ovaries, so your estrogen ( one of the hormones that cause your body to have periods ) grade is lowered. After your first base injection ( dart ), your estrogen level will rise before it goes down. This is called an “ estrogen scend ”. Because of this rise in estrogen, you may have an increase in your symptoms for a few weeks. After the estrogen surge, your estrogen levels will go down. This temporarily stops your period. When you do not have periods, endometriosis symptoms are normally relieved .

How is Leuprolide acetate given?

Leuprolide acetate is an injection. It is very important to get your injection on time. miss doses can cause breakthrough bleed and the render of trouble .

How long can I take Leuprolide acetate with add–back?

Leuprolide acetate rayon alone is normally prescribed for 6 months ( 1 shoot every 3 months ). however, when you take it with add–back, you can about always stay on it longer. After a few months of treatment, you will have an date with your gynecologist to see if the medicine is helping you. This date besides gives your doctor a find to ask you about your pelvic pain and any early symptoms you may be having. If your symptoms are well, he may suggest that you continue taking the medicate.

What are the side effects of taking Leuprolide acetate?

Taking Leuprolide acetate rayon alone lowers the estrogen level in the body, which typically causes side effects similar to menopause. These side effects may include : hot flashes, vaginal dryness, decreased interest in arouse, moodiness, headaches, spotting, and change in bone concentration. however, with the addition of “ add–back ” therapy, you will most likely NOT experience these side effects. If you do have symptoms, they are generally balmy. After the second calendar month of discussion, your period will probably stop. however, you may have a light up menstruation or spotting during treatment. It is crucial to get your injections on time and to stop discussion when recommended .

What is “Add–back” therapy?

Add–back is a pill that contains a humble sum of estrogen and progestin or progestin–only that is taken every day. Since hormones are crucial to keep your bones healthy, first gear levels of hormones can lower your cram concentration putting you at hazard for osteoporosis ( thinning of your bones ). The goal of add–back therapy is to give your body back good adequate hormone ( s ) to protect your bones and control any unwanted side effects such as hot flashes and vaginal dryness that are park when taking Leuprolide acetate alone. Your gynecologist will decide on how much add–back music you will need, and give you a prescription. Add–back is either : Aygestin® 5mg/daily, or Prempro® 0.625/2.5mg/daily .

When do the effects of Leuprolide acetate go away?

The effects of Leuprolide acetate rayon will decrease after you stop taking the medicine. If you ’ ve been getting Lupron® every 3 months, your period will normally return within 4 to 8 months after your last shot. If you ’ ve been getting Lupron Depot® every calendar month, your period will likely return 6–8 weeks after your death blastoff. Bone concentration loss may be partially or completely recovered. This means that your bones may or may not be a solid as they were before you started the music.

Can I take Leuprolide acetate forever?

research has shown that long condition use of Leuprolide acetate alone can cause cram density loss. Bone concentration loss is a big business particularly if you have a syndicate history of osteoporosis. Osteoporosis causes your bones to become flimsy and break more easily. “ Add–back ” therapy can help prevent loss of bone density, which may allow you to stay on the music long .

What is bone density?

Bone concentration is a measurement of how solid and strong your bones are. Bones need to be strong and solid so they do not break easily. Your adolescent and unseasoned adult years are important for bone exploitation. Weak bones during the adolescent years may negatively impact your bone health later in biography. Your bones need lots of nutrients, particularly calcium and vitamin D. It is besides crucial to eat a well–balanced diet and include foods high in calcium .

When will I be scheduled for a bone density test?

After you have been on Leuprolide acetate rayon for approximately 6-8 months, your will order a cram concentration scan ( DXA test ). This is a childlike test that measures how dense ( or thick ) your bones are and if your bones are thinning. If the DXA scan is normal and you continue on the medicine, you will need to repeat the DXA quiz every 1-2 years.

What can I do to prevent bone loss?

You will probable be told to take calcium and vitamin D supplements. calcium works to build and maintain cram density. Vitamin D improves the absorption of calcium. Make certain to divide your daily dose of calcium if taking more than 500mg. Your torso can entirely absorb therefore much at once. If you take a calcium accessory with vitamin D, make sure it contains at least 800 of vitamin D .

Can I get pregnant when I am on Leuprolide acetate?

Although this medicine works by preventing ovulation ( stops you from making eggs ), there is a rare find that you could become meaning if you have unprotected sex. therefore, it is authoritative to use a non–hormonal birth control method such as condoms while on this medication. The long-run effects to an unborn pamper whose mother was on Leuprolide acetate at the time of invention are unknown at this clock, but it does not appear to cause parentage defects. Remember, all medicine affects people differently. If you have side effects, talk with your GYN team. It normally takes 2–3 months to see an improvement in symptoms and for your body to get used to the medicine. In the meanwhile, you can help your body feel well by eating well and getting enough of rest and exert .

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